Life Science Lab Feasibility Study in Massachusetts

What SBA's own loan files show about life science lab (research and development) lending in Massachusetts, and what a feasibility study for a project there has to test.

A leading state for a small class

Massachusetts ranks 2 of 41 among states for research and development lending in the life science lab class, a position set beside the class's middling standing inside the state, 21 of 39 among asset classes. The reconciliation is the location quotient: at 3.09x, laboratory businesses take a much larger share of Massachusetts SBA loans than of the national book. The count is small, 31 loans worth $13.0 million from FY2017 to FY2026, so the ranking reflects how large the class is relative to Massachusetts lending overall and not the volume of loans.

Loan size and where the work sits

Lab loans in Massachusetts are light. The median is $195,900, which works out to 0.78x of the class median nationwide, and the middle half spans $100,000 to $350,000. The record does not say what the money bought, but tickets of this size are small beside the cost of building a purpose-built laboratory. Middlesex County accounts for 13 loans and Worcester for 9, with Essex at 3 and Bristol and Norfolk at 2 each. Of the 31 loans, 27 ran through the 7(a) program and just 4 through 504, and none is flagged as a franchise.

The lenders the record names

Webster Five Cents Savings Bank holds 6 loans worth $3.4 million under SBA 7(a), and Rockland Trust Company holds 5 worth $1.9 million. SBA lists these as loans each institution holds or held, which shows where the class has been financed and says nothing about any bank's current appetite.

What the code does not isolate

What the code captures is the research firm, never the laboratory building itself. The same code also holds research that is not life science, so the 31 loans can include firms of more than one kind, and the cell cannot tell a wet-lab owner from a software-only researcher. The cancellation and charge-off rates are held back because fewer than 30 loans sit in their cohorts; that is Loan Analytics' own presentation rule, and held back does not mean zero.

Testing a Massachusetts lab project

A feasibility study for a life science lab in Massachusetts should test whether the tenant or owner truly needs wet-lab space, since ventilation, power and floor loading are what separate a lab from ordinary offices and what drive cost. It should compare the build-out budget to a loan record centred on small tickets, show how revenue or grant timing supports debt service, and have the appraiser address how readily a specialised space re-lets if the first occupant leaves. Revenue and grant receipts can arrive unevenly, so the study needs a downside case in which a milestone slips.

SBA 7(a) and 504 life science lab (research and development) loans in Massachusetts

Loans approved, FY2017 to FY202631
Gross dollars approved$13.0 million
Median loan$195,900
Middle half of loans, from$100,000
Middle half of loans, to$350,000
SBA 7(a) loans27
SBA 504 loans4
Franchise share of loans0.00%
Rank among states for life science lab (research and development) loans2 of 41
Rank of life science lab (research and development) among classes in Massachusetts21 of 39
Location quotient (share of loans against the national share)3.09x
Median loan against the national median for the class0.78x

Cancellation and charge-off

Cancelled after approval, FY2017 to FY2024 approvals (a floor) not reported: fewer than 30 loans in the cohort
Charged off to date, FY2017 to FY2021 disbursed loans (a floor) not reported: fewer than 30 loans in the cohort

Both rates are floors. SBA withholds the status of open loans, so a loan counts as charged off only once SBA reports it; a rate needs at least 30 loans in its cohort and is otherwise not reported.

SBA 7(a) and 504 life science lab (research and development) loans approved in Massachusetts, by fiscal year

0246FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025FY2026Loans, FY2017: 3Loans, FY2018: 2Loans, FY2019: 0Loans, FY2020: 3Loans, FY2021: 2Loans, FY2022: 6Loans, FY2023: 2Loans, FY2024: 5Loans, FY2025: 5Loans, FY2026: 3
Fiscal yearLoansDollars
FY20173$650,000
FY20182$231,000
FY20190$0
FY20203$1.6 million
FY20212$2.0 million
FY20226$1.0 million
FY20232$4.0 million
FY20245$1.4 million
FY20255$1.8 million
FY20263$319,700

Most active SBA lenders

SBA 7(a): lenders by loans approved (the current holder of each loan, as SBA reports it)
LenderLoansDollars
Webster Five Cents Savings Bank6$3.4 million
Rockland Trust Company5$1.9 million

Where the loans are, by county

CountyLoans
MIDDLESEX13
WORCESTER9
ESSEX3
BRISTOL2
NORFOLK2
HAMPDEN1
HAMPSHIRE1

The code is the research business, not the lab building; 541715 also holds non-life-science research.

Source: U.S. Small Business Administration, 7(a) and 504 loan-level FOIA files (data.sba.gov), as of 2026-09-30; Loan Analytics loan-outcome cell SA-MA-C26.

Loan Analytics prepares the feasibility study a lender reads before it commits: for a life science lab (research and development) project in Massachusetts, financed under SBA 7(a), SBA 504, USDA Business and Industry or a conventional bank loan. Tell us the project and the lender's deadline, and we reply with scope, timeline and fee.

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