SBA 7(a) Life Science Lab Feasibility Study

The national SBA 7(a) record for life science lab (research and development) projects, from SBA's loan-level files, and what a lender's feasibility study has to test.

Research businesses, not lab buildings

The 7(a) life science class records 292 loans and $143.4 million from FY2017 to FY2026, but its limitation matters more than usual: the code identifies a research business, not a lab building, and it also holds research outside the life sciences. The loans look like it. The median is $235,000, and the middle half runs from $83,000 to $500,000, working capital and equipment sizes, not the cost of a wet lab. Nothing here clears our distinctness margin against the 7(a) program or the class across both programs.

Newtek Bank, National Association leads the lender table with 24 loans and $15.0 million. Wells Fargo Bank National Association has 23 loans for just $1.1 million, The Huntington National Bank 21 for $5.3 million, and both TD Bank, National Association ($1.6 million) and JPMorgan Chase Bank, National Association ($3.2 million) have 11 each. California has 36 loans, Florida and Massachusetts 27 each, Texas 24 and Ohio 17. Volume rose from 17 loans in FY2018 to 51 in FY2025, and FY2026 brought the top dollar year at $24.3 million. Franchise share is 1.0%.

Early losses

Cancellation sits at 11.0% at minimum and 12.4% at most. Of the 108 research loans that funded in FY2017 to FY2021, 3.7% or more were charged off, 2.8% inside five years, so most losses came early, which fits businesses whose revenue depends on grants, contracts or a product that may not reach market. A borrower should expect a lender to look past the research label to the customer list and the signed contracts behind it.

What a research business study must test

A feasibility study behind a 7(a) loan here has to test where revenue comes from, whether contract research, grants, product sales or milestone payments, and how concentrated it is in a few clients; the cost of equipment and lab fit-out, which may be specialized and hard to resell; debt service coverage from contracted revenue rather than pipeline; and, if a building is part of the deal, an appraisal of the lab or flex space that tests demand from other research tenants. For a lender, the study's job is to separate a business with paying customers from one still spending toward its first.

SBA 7(a) life science lab (research and development) loans in the United States

Loans approved, FY2017 to FY2026292
Gross dollars approved$143.4 million
Median loan$235,000
Middle half of loans, from$83,000
Middle half of loans, to$500,000
Franchise share of loans1.0%

Cancellation and charge-off

Cancelled after approval, FY2017 to FY2024 approvals (a floor) 11.0%
The same, counting loans still undisbursed as cancelled (a ceiling)12.4%
Charged off to date, FY2017 to FY2021 disbursed loans (a floor) 3.7%
Charged off within five years of approval2.8%
Loans in that cohort108

Both rates are floors. SBA withholds the status of open loans, so a loan counts as charged off only once SBA reports it; a rate needs at least 30 loans in its cohort and is otherwise not reported.

SBA 7(a) life science lab (research and development) loans approved in the United States, by fiscal year

0204060FY2017FY2018FY2019FY2020FY2021FY2022FY2023FY2024FY2025FY2026Loans, FY2017: 21Loans, FY2018: 17Loans, FY2019: 31Loans, FY2020: 28Loans, FY2021: 20Loans, FY2022: 30Loans, FY2023: 22Loans, FY2024: 40Loans, FY2025: 51Loans, FY2026: 32
Fiscal yearLoansDollars
FY201721$6.9 million
FY201817$5.0 million
FY201931$11.3 million
FY202028$15.9 million
FY202120$9.1 million
FY202230$17.9 million
FY202322$14.6 million
FY202440$21.1 million
FY202551$17.4 million
FY202632$24.3 million

Most active SBA lenders

SBA 7(a): lenders by loans approved (the current holder of each loan, as SBA reports it)
LenderLoansDollars
Newtek Bank, National Association24$15.0 million
Wells Fargo Bank National Association23$1.1 million
The Huntington National Bank21$5.3 million
JPMorgan Chase Bank, National Association11$3.2 million
TD Bank, National Association11$1.6 million

Where the loans are, by state

StateLoans
California36
Florida27
Massachusetts27
Texas24
Ohio17
Illinois11
North Carolina11
Washington11
Pennsylvania10
Colorado9

The code is the research business, not the lab building; 541715 also holds non-life-science research.

Source: U.S. Small Business Administration, 7(a) and 504 loan-level FOIA files (data.sba.gov), as of 2026-09-30; Loan Analytics loan-outcome cell PA-C26-7A.

Loan Analytics prepares the feasibility study a lender reads before it commits: for a life science lab (research and development) project anywhere in the United States, financed under SBA 7(a), SBA 504, USDA Business and Industry or a conventional bank loan. Tell us the project and the lender's deadline, and we reply with scope, timeline and fee.

Request Scope & Timeline

Start with the data.

Contact Us